Research focus

The research group is focused on the development of nuclear magnetic resonance (NMR), revealing binding and spatial arrangements of atoms in molecular and supramolecular systems. We develop theoretical concepts and pursue various practical applications. The subjects of our investigation are biologically active coordination compounds of transition metals including antitumor metallodrugs based on platinum and ruthenium and magnetic resonance imaging (MRI) contrast agents containing lanthanides. Synthesized metallocomplexes are further mixed with macrocyclic carriers resulting in supramolecular inclusion complexes of enhanced biological activity. To determine and predict the NMR shifts of light atoms in paramagnetic coordination compounds, binding affinity of metallodrugs to transport systems, and supramolecular arrangements of complex systems, experimental NMR measurements are complemented by DFT calculations and methods of molecular modelling.

For students

As part of ongoing research and pedagogical activities, we offer cooperation in independent projects; final projects (students of the programme Chemistry) and bachelor's (students of the programme Chemistry with a view to Education), diploma and doctoral theses. Working on pedagogical topics in physical chemistry, metallic materials or computational modeling is also possible. We will be happy to show you our workplace and discuss the possibilities of involvement in our activities.

Head of the research group

If you are interested in any information, please do not hesitate to contact the group leader.